Father Guido Sarducci hosted two Saturday Night LIve episodes during the 1983-1984 season and cameoed during two 1990s episodes. All together, Father Sarducci appeared on Saturday Night Live thirty-one times, the most of any of the recurring characters.

On March 19, 2005, Father Sarducci appeared on the MSNBC show Countdown with Keith Olbermann discussing The Da Vinci Code and his DaVinci Code Decoder Ring.