“Comedy’s not a science. Science isn’t a science.
We’re learning that all the time. Nobody knows, really, 
what they’re doing. [audience laughter]  They don’t!
They don’t know what they’re doing!
And there’s two ways to go with that information.
One is to be afraid and the other is to be liberated.
And I choose to be liberated by it.”

– Conan O’Brien,
Inside the Actors Studio